In vivo synergism of roxithromycin (RU 965) and interferon against Toxoplasma gondii.
نویسندگان
چکیده
We investigated the activity of roxithromycin (RU 965) and gamma interferon alone and in combination in a murine model of toxoplasmic encephalitis. Roxithromycin at a dosage of 35 or 50 mg per mouse per day decreased mortality. Gamma interferon alone significantly prolonged time to death. When combined, the two agents were remarkably synergistic.
منابع مشابه
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 31 2 شماره
صفحات -
تاریخ انتشار 1987